We tend to think that everything important comes from the centre: from big cities, from established orthodoxies in the sciences and the arts, from the Establishment in all its forms. We think this because the centre tells us it is so, but it’s a lie. It is only at the edges that we think, innovate and thrive. This book travels to the frontiers of human culture and consciousness; to the edges of continents, of evolution, of artistic and political movements, and life itself: from a rocky precipice in the Peloponnese where the first human set foot in Europe to an ancient Egyptian temple where monotheism was invented; from St Francis, kissing lepers to the giant bird-eating mice of St Kilda.